Orally administered beraprost sodium inhibits pulmonary hypertension induced by monocrotaline in rats.

@article{Yuki1994OrallyAB,
  title={Orally administered beraprost sodium inhibits pulmonary hypertension induced by monocrotaline in rats.},
  author={Hidetaka Yuki and Shuichi Sato and Yoshifumi Arisaka and Shigeki Kato and Hitonobu Tomoike},
  journal={The Tohoku journal of experimental medicine},
  year={1994},
  volume={173 4},
  pages={371-5}
}
Rats were fed on distilled water (DW) or DW containing beraprost sodium (BPS). BPS concentration was 1.5 or 3.0 mu/ml in DW for the low BPS groups and 6.0 or 10.0 mu/ml in DW for the high BPS group. Monocrotaline (MCT) was subcutaneously given (60 mg/kg), and saline was injected as control. Data were analyzed among the following groups; Groups (Saline + DW… CONTINUE READING