Orally Formulated Artemisinin in Healthy Fasting Vietnamese Male Subjects: A Randomized, Four-Sequence, Open-Label, Pharmacokinetic Crossover Study

Abstract

BACKGROUND Artemisinin derivatives are used in antimalarial drug combination therapy. Artemisinin and piperaquine have recently been proven to be prospective candidates for combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. OBJECTIVE The goal of this study was to evaluate the relative bioavailability and to characterize… (More)
DOI: 10.1016/j.clinthera.2011.04.017

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