Orally Administered Melatonin Prevents Lipopolysaccharide-Induced Neural Tube Defects in Mice

Abstract

Lipopolysaccharide (LPS) has been associated with adverse pregnant outcomes, including fetal demise, intra-uterine growth restriction (IUGR), neural tube defects (NTDs) and preterm delivery in rodent animals. Previous studies demonstrated that melatonin protected against LPS-induced fetal demise, IUGR and preterm delivery. The aim of the present study was… (More)
DOI: 10.1371/journal.pone.0113763

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Cite this paper

@inproceedings{Fu2014OrallyAM, title={Orally Administered Melatonin Prevents Lipopolysaccharide-Induced Neural Tube Defects in Mice}, author={Lin Fu and Zhen Yu and Yuan-hua Chen and Mi-Zhen Xia and Huimin Wang and Cheng Zhang and Fang-biao Tao and De-Xiang Xu}, booktitle={PloS one}, year={2014} }