Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials.

@article{Ferrari2001OralT,
  title={Oral triptans (serotonin 5-HT(1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials.},
  author={Michel D. Ferrari and Krista I Roon and Richard B. Lipton and Peter J Goadsby},
  journal={Lancet},
  year={2001},
  volume={358 9294},
  pages={1668-75}
}
BACKGROUND The triptans, selective serotonin 5-HT(1B/1D) agonists, are very effective acute migraine drugs with a well- developed scientific rationale. Seven different triptans will soon be clinically available, making evidence-based selection guidelines necessary. Triptan trials have similar designs, facilitating meta-analysis; this will provide a foundation for using triptans in clinical practice. METHOD We asked pharmaceutical companies and the principal investigators of company… CONTINUE READING
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