Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

@article{Varhe1994OralTI,
  title={Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole},
  author={Anu Varhe and Klaus T. Olkkola and Pertti J. Neuvonen},
  journal={Clinical Pharmacology \& Therapeutics},
  year={1994},
  volume={56}
}
Triazolam is metabolized by CYP3A4 isozyme. Ketoconazole and itraconazole may seriously interact with some of the substrates of CYP3A4 (e.g., terfenadine); hence their possible interaction with triazolam in humans is important to uncover. 

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