Oral treatment with genistein reduces the expression of molecular and biochemical markers of inflammation in a rat model of chronic TNBS-induced colitis.

@article{Seibel2009OralTW,
  title={Oral treatment with genistein reduces the expression of molecular and biochemical markers of inflammation in a rat model of chronic TNBS-induced colitis.},
  author={Jan Seibel and Almut F. Molzberger and Torsten Hertrampf and Ute Laudenbach-Leschowski and Patrick Diel},
  journal={European journal of nutrition},
  year={2009},
  volume={48 4},
  pages={213-20}
}
BACKGROUND Inflammatory bowel disease (IBD) in humans has a high incidence in Europe and the USA, whereas in East Asia, incidence has been historically low. The risk of IBD appears to increase in Asian immigrants adopting western lifestyles, suggesting a strong link of environmental/dietary factors in the development of IBD. Exposure to high levels of isoflavones such as genistein (Gen) in traditional East Asian diets has been associated with a decreased risk of developing breast cancer and may… CONTINUE READING

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