Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial.

@article{Johnson2004OralTR,
  title={Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial.},
  author={Bankole A Johnson and Nassima Ait-Daoud and Fatema Z. Akhtar and Jennie Z Ma},
  journal={Archives of general psychiatry},
  year={2004},
  volume={61 9},
  pages={
          905-12
        }
}
BACKGROUND Topiramate, a fructopyranose derivative, was superior to placebo at improving the drinking outcomes of alcohol-dependent individuals. OBJECTIVES To determine whether topiramate, compared with placebo, improves psychosocial functioning in alcohol-dependent individuals and to discover how this improvement is related to heavy drinking behavior. DESIGN Double-blind, randomized, controlled, 12-week clinical trial comparing topiramate vs placebo for treating alcohol dependence (1998… CONTINUE READING
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