Oral sex is associated with reduced incidence of recurrent miscarriage.

@article{Meuleman2019OralSI,
  title={Oral sex is associated with reduced incidence of recurrent miscarriage.},
  author={Tess Meuleman and N Baden and Geert W. Haasnoot and Marise M Wagner and Olaf M. Dekkers and Saskia le Cessie and Charles Picavet and Jan M M van Lith and Frans H. J. Claas and Kitty W. M. Bloemenkamp},
  journal={Journal of reproductive immunology},
  year={2019},
  volume={133},
  pages={
          1-6
        }
}
A possible way of immunomodulation of the maternal immune system before pregnancy would be exposure to paternal antigens via seminal fluid to oral mucosa. We hypothesized that women with recurrent miscarriage have had less oral sex compared to women with uneventful pregnancy. In a matched case control study, 97 women with at least three unexplained consecutive miscarriages prior to the 20th week of gestation with the same partner were included. Cases were younger than 36 years at time of the… 
4 Citations
Regulatory T Cells in Pregnancy: It Is Not All About FoxP3
TLDR
There appears to be great diversity within the Treg population during pregnancy, both at the maternal-fetal interface as in the peripheral blood, which suggests that distinct Treg subsets play a role at different time points of gestation and that their role in maintaining healthy pregnancy is crucial.
Oral tolerance and the materno-fetal relationship.
  • D. Clark
  • Medicine
    Journal of reproductive immunology
  • 2019
TLDR
Issues relating to assessing the applicability of oral exposure to seminal plasma antigens in recurrent miscarriage are discussed and such tolerance could represent an unappreciated confounder in immunotherapy trials.

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