Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies

@inproceedings{Prins2013OralRV,
  title={Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies},
  author={Martin H. Prins and Anthonie W. A. Lensing and Rupert Martin Bauersachs and Bonno van Bellen and Henri Bounameaux and Timothy A Brighton and Alexander A. Cohen and Bruce L Davidson and Herv{\'e} D{\'e}cousus and Gary E. Raskob and Scott D. Berkowitz and Philip S Wells},
  booktitle={Thrombosis journal},
  year={2013}
}
BACKGROUND Standard treatment for venous thromboembolism (VTE) consists of a heparin combined with vitamin K antagonists. Direct oral anticoagulants have been investigated for acute and extended treatment of symptomatic VTE; their use could avoid parenteral treatment and/or laboratory monitoring of anticoagulant effects. METHODS A prespecified pooled analysis of the EINSTEIN-DVT and EINSTEIN-PE studies compared the efficacy and safety of rivaroxaban (15 mg twice-daily for 21 days, followed by… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Related Discussions
This paper has been referenced on Twitter 8 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 146 extracted citations

Real-World Medical Cost Avoidance When New Oral Anticoagulants are Used Versus Warfarin for Venous Thromboembolism in the United States.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis • 2016
View 10 Excerpts
Highly Influenced

Dabigatran for the treatment of venous thromboembolism.

Expert review of hematology • 2015
View 9 Excerpts
Highly Influenced

Treatment options for venous thromboembolism: lessons learnt from clinical trials

Thrombosis journal • 2014
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 21 references

Apixaban for extended treatment of venous thromboembolism.

The New England journal of medicine • 2013
View 1 Excerpt

Lensing AWA: Derivation of the non-inferiority margin for the evaluation of direct oral anticoagulants in the treatment of venous thromboembolism

MH Prins
Thromb J • 2013

No need for a rivaroxaban dose reduction in renally impaired patients with symptomatic venous thromboembolism [abstract

R Bauersachs, AWA Lensing, A Pap, H Decousus
J Thromb Haemost • 2013
View 1 Excerpt

MH: Benchmark for time in therapeutic range in venous thromboembolism: a systematic review and met a-analysis

PM Erkens, H Ten Cate, HR Buller, Prins
PLoS • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…