Oral rivaroxaban versus enoxaparin with vitamin K antagonist for the treatment of symptomatic venous thromboembolism in patients with cancer (EINSTEIN-DVT and EINSTEIN-PE): a pooled subgroup analysis of two randomised controlled trials.

@article{Prins2014OralRV,
  title={Oral rivaroxaban versus enoxaparin with vitamin K antagonist for the treatment of symptomatic venous thromboembolism in patients with cancer (EINSTEIN-DVT and EINSTEIN-PE): a pooled subgroup analysis of two randomised controlled trials.},
  author={Martin H. Prins and Anthonie W. A. Lensing and Tim A. Brighton and Roger M. Lyons and Jeffrey Rehm and Mila Trajanovic and Bruce L Davidson and Jan Beyer-Westendorf and {\'A}kos Ferenc Pap and Scott D. Berkowitz and Alexander A. Cohen and Michael J. Kovacs and Philip S Wells and Paolo Prandoni},
  journal={The Lancet. Haematology},
  year={2014},
  volume={1 1},
  pages={e37-46}
}
BACKGROUND Patients with venous thromboembolism and cancer have a substantial risk of recurrent venous thromboembolism and bleeding during anticoagulant therapy. Although monotherapy with low-molecular-weight heparin is recommended in these patients, in clinical practice many patients with venous thromboembolism and cancer do not receive this treatment. We aimed to assess the efficacy and safety of a single-drug regimen with oral rivaroxaban compared with enoxaparin followed by vitamin K… CONTINUE READING

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