Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections

@inproceedings{Conti2014OralresidentNT,
  title={Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections},
  author={Heather R Conti and Alanna Carol Peterson and Lucas B Brane and Anna R. Huppler and Nydiaris Hern{\'a}ndez-Santos and Natasha Whibley and Abhishek V. Garg and Michelle R. Simpson-Abelson and Gregory A. Gibson and Anna J. Mamo and Lisa Colleen Osborne and Shrinivas Bishu and Nico Ghilardi and Ulrich Siebenlist and Simon C. Watkins and David Artis and Mandy J McGeachy and Sarah L Gaffen},
  booktitle={The Journal of experimental medicine},
  year={2014}
}
Oropharyngeal candidiasis (OPC) is an opportunistic fungal infection caused by Candida albicans. OPC is frequent in HIV/AIDS, implicating adaptive immunity. Mice are naive to Candida, yet IL-17 is induced within 24 h of infection, and susceptibility is strongly dependent on IL-17R signaling. We sought to identify the source of IL-17 during the early innate… CONTINUE READING