Oral rehydration for viral gastroenteritis in adults: a randomized, controlled trial of 3 solutions.

@article{Rao2006OralRF,
  title={Oral rehydration for viral gastroenteritis in adults: a randomized, controlled trial of 3 solutions.},
  author={S. S. Rao and Robert W. Summers and G R S Rao and S. Ramana and Uma P Devi and Bridget M. Zimmerman and B. Pratap},
  journal={JPEN. Journal of parenteral and enteral nutrition},
  year={2006},
  volume={30 5},
  pages={
          433-9
        }
}
BACKGROUND Pedialyte and Gatorade are advocated for the treatment of dehydration in viral gastroenteritis, but there is limited evidence to support their use. We examine the efficacy, safety, and palatability of Pedialyte, Gatorade, and a New Oral Rehydration Solution (N-ORS). This was a randomized double-blind trial conducted in an inpatient, community hospital. Seventy-five consecutive adult patients (male, 42; female, 33) admitted with viral gastroenteritis were randomized to receive… 

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References

SHOWING 1-10 OF 15 REFERENCES

Use of a single solution for oral rehydration and maintenance therapy of infants with diarrhea and mild to moderate dehydration.

The two maintenance oral electrolyte solutions most commonly used in the United States are effective as rehydration solutions for infants with mild to moderate dehydration and might gain additional acceptance by practicing pediatricians and family physicians.

Clinical trial of glucose-oral rehydration solution (ORS), rice dextrin-ORS, and rice flour-ORS for the management of children with acute diarrhea and mild or moderate dehydration.

It is concluded that the three solutions had similar efficacy for children with acute, watery diarrhea and mild or moderate dehydration.

Safety and effectiveness of homemade and reconstituted packet cereal-based oral rehydration solutions: a randomized clinical trial.

CBORS do not offer a clinically significant advantage over glucose-based ORS, but it is not the safest alternative for regular clinical use.

Sodium content of oral rehydration solutions: a reappraisal.

In controlled clinical trials, oral rehydration solutions with 50-60 mmol/1 sodium have proven safe, and performance was compatible with WHO-ORS, and the solution proved effective for both reHydration and correction of acidosis.

Validity and reliability of clinical signs in the diagnosis of dehydration in children.

Conventionally used clinical signs of dehydration are valid and reliable; however, individual findings lack sensitivity and should be based on the presence of at least three clinical findings.

The Role of Oral Rehydration Solutions in the Children of Europe: Continuing Controversies

The role of oral rehydration solutions in the children of Europe‐ Continuing controversies is investigated to assess the need for further studies on the basis of available literature and anecdotal evidence.

Increasing prevalence of recurrent otitis media among children in the United States.

There has been a significant increase in the prevalence of recurrent otitis media among children in the United States, particularly in infants, and the increased prevalence was associated with an increase with the use of child care and a higher prevalence of allergic conditions among children.

Intestinal Electrolyte Transport and Diarrheal Disease

Enteric organisms cause diarrhea in several ways, some of which are noninvasive but secrete toxins that interact with intestinal epithelial cells to stimulate fluid secretion (e.g., cholera); others invade and destroy intestinal epithelium cells, thereby altering fluid transport.

Effects of carbohydrate type and concentration and solution osmolality on water absorption.

It is suggested that solutions with multiple substrates produce greater water absorption at a given osmolality than those with one, and several different solute absorption mechanisms yielding greaterWater absorption than solutions with only one substrate.