Oral psoralen and ultraviolet-A light (PUVA) treatment of psoriasis and persistent risk of nonmelanoma skin cancer. PUVA Follow-up Study.

@article{Stern1998OralPA,
  title={Oral psoralen and ultraviolet-A light (PUVA) treatment of psoriasis and persistent risk of nonmelanoma skin cancer. PUVA Follow-up Study.},
  author={R S Stern and E J Liebman and Liisa V{\"a}kev{\"a}},
  journal={Journal of the National Cancer Institute},
  year={1998},
  volume={90 17},
  pages={1278-84}
}
BACKGROUND/METHODS The treatment of psoriasis with high-dose exposure to oral psoralen and ultraviolet-A light (i.e., PUVA) substantially increases the risk of cutaneous squamous cell cancer, but not of basal cell cancer, within a decade of beginning treatment. To assess the persistence of cancer risk among individuals treated with PUVA, including those who discontinued therapy long ago and those without substantial exposure to other carcinogens, we prospectively studied a cohort of 1380… CONTINUE READING

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