Oral osteonecrosis associated with the use of ibandronate: report of a case and clinical implications.

@article{Migliorati2008OralOA,
  title={Oral osteonecrosis associated with the use of ibandronate: report of a case and clinical implications.},
  author={C{\'e}sar Augusto Migliorati and Basil N Armonis and Ourania Nicolatou-Galitis},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2008},
  volume={106 1},
  pages={e18-21}
}
A breast cancer patient with skeletal metastases was treated with only one i.v. dose of ibandronate in March of 2005 and subsequent doses of oral ibandronate 50 mg daily. One year after the i.v. infusion, the patient complained of oral pain under her lower denture. After several negative attempts from her dentist to control the pain and adjust the denture, the patient was diagnosed with bisphosphonate-associated osteonecrosis (BON) of the mandible. The use of ibandronate, a potent… CONTINUE READING

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