Oral mucosal ulceration in systemic lupus erythematosus.

  title={Oral mucosal ulceration in systemic lupus erythematosus.},
  author={Jorge Urman and M. B. Lowenstein and Micha Abeles and Arthur Weinstein},
  journal={Arthritis and rheumatism},
  volume={21 1},
In 182 patients with systemic lupus erythematosus (SLE), oral mucosal ulceration occurred in 47 patients (26%), was usually painless (82%), and most often involved the hard palate (89%). Oral ulceration was associated with an increase in overall clinical activity, although this was not accompanied by significant changes in the levels or titers of C3, anti-DNA antibodies, and anti-nuclear antibodies. Necrotizing vasculitis was not observed. Microscopic changes were similar to the skin lesions of… CONTINUE READING


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