Oral manifestations and their treatment in Sjögren's syndrome.

@article{Gonzlez2014OralMA,
  title={Oral manifestations and their treatment in Sj{\"o}gren's syndrome.},
  author={S. Gonz{\'a}lez and H. Sung and D. Sep{\'u}lveda and M.-J. Gonz{\'a}lez and C. Molina},
  journal={Oral diseases},
  year={2014},
  volume={20 2},
  pages={
          153-61
        }
}
Sjögren's syndrome (SS) is a complex, chronic, systemic, autoimmune disease that mainly affects the exocrine glands, especially the salivary and lacrimal glands, leading to dryness of the oral and ocular mucosae. Several factors have been studied that could explain the glandular hypofunction primarily related to water transport. Recent reports have shown alterations in secretory route and trafficking in labial salivary glands, explaining alterations in the saliva quality. The decrease in… Expand
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References

SHOWING 1-10 OF 121 REFERENCES
The oral side of Sjögren syndrome. Diagnosis and treatment. A review.
TLDR
The role of the oral tests developed to diagnose SS is assessed, especially tests used by the majority of criteria, and therapeutic modalities designed to ameliorate these damages by increasing salivary output or by substitution of saliva are reviewed. Expand
Treatment of oral dryness related complaints (xerostomia) in Sjögren’s syndrome
TLDR
This review describes the current clinical manifestations of the oral component of SS, a systemic autoimmune disorder characterised by a chronic, progressive loss of salivary and lacrimal function resulting in symptoms of oral and ocular dryness. Expand
Oral dryness in Sjögren's syndrome patients. Not just a question of water.
TLDR
Parts of reduced salivary flow and decreased quality of Salivary mucins are focused on, since they are likely to be responsible for xerostomia in SS-patients. Expand
Clinical manifestations and early diagnosis of Sjögren syndrome.
TLDR
Armed with the recently refined criteria for diagnosis, specialists, such as rheumatologists, primary care physicians, ophthalmologists, and dentists, who would otherwise focus only on those symptoms that encompass their areas of expertise, can get a comprehensive image of the presenting patient, leading to earlier identification and treatment of SS. Expand
The geoepidemiology of Sjögren's syndrome.
TLDR
Although the clinical manifestations of pSS patients are mainly those of an autoimmune exocrinopathy, almost half of patients develop extraglandular disease, which may be manifested either by epithelial lymphocytic invasion of lung, liver, or kidney (resulting in interstitial nephritis) or by skin vasculitis, peripheral neuropathy, glomerulonephritis, and low C4 levels. Expand
Primary Sjögren's syndrome (pSS): subjective symptoms and salivary findings.
  • A. Pedersen, J. Reibel, B. Nauntofte
  • Medicine
  • Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • 1999
TLDR
RATING of oral dryness by visual analogue scales or categorised questionnaires is considered to be valuable for the evaluation of oral involvement in pSS. Expand
Primary Sjögren syndrome
TLDR
The authors wish to call attention to the methodology used in accurately diagnosing SS and to illustrate its signs and symptoms with a case report. Expand
Update in Sjögren syndrome.
TLDR
Even in SS patients with marked sicca symptoms, minor salivary gland biopsy shows that almost 50% of glandular cells are still detected on biopsy, implying the importance of immune factors such as cytokines and autoantibodies in decreasing neuro-secretory circuits and induction of glandsular dysfunction. Expand
Periodontal conditions of individuals with Sjögren's syndrome.
TLDR
SjS seemed to negatively affect the periodontal condition because gingival inflammation was more evident in the individuals with SjS, particularly those with SJS (S). Expand
The role of intrinsic epithelial activation in the pathogenesis of Sjögren's syndrome.
Sjögren's syndrome (SS) is a chronic autoimmune disorder that is characterized by dysfunction and destruction of the exocrine glands. Exocrinopathy is associated with periductal mononuclear cellExpand
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