Oral low dose and topical tamoxifen for breast cancer prevention: modern approaches for an old drug

@article{Lazzeroni2012OralLD,
  title={Oral low dose and topical tamoxifen for breast cancer prevention: modern approaches for an old drug},
  author={M. Lazzeroni and D. Serrano and B. Dunn and B. Heckman-Stoddard and O. Lee and Seema A. Khan and A. Decensi},
  journal={Breast Cancer Research : BCR},
  year={2012},
  volume={14},
  pages={214 - 214}
}
Tamoxifen is a drug that has been in worldwide use for the treatment of estrogen receptor (ER)-positive breast cancer for over 30 years; it has been used in both the metastatic and adjuvant settings. Tamoxifen's approval for breast cancer risk reduction dates back to 1998, after results from the Breast Cancer Prevention Trial, co-sponsored by the National Cancer Institute and the National Surgical Adjuvant Breast and Bowel Project, showed a 49% reduction in the incidence of invasive, ER… Expand
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