Oral leucine administration stimulates protein synthesis in rat skeletal muscle.

@article{Crozier2005OralLA,
  title={Oral leucine administration stimulates protein synthesis in rat skeletal muscle.},
  author={Stephen J. Crozier and Scot R. Kimball and Sans W Emmert and Joshua C. Anthony and Leonard S. Jefferson},
  journal={The Journal of nutrition},
  year={2005},
  volume={135 3},
  pages={376-82}
}
Oral administration of a single bolus of leucine in an amount equivalent to the daily intake (1.35 g/kg body wt) enhances skeletal muscle protein synthesis in food-deprived rats. To elucidate whether smaller amounts of leucine can also stimulate protein synthesis, rats were administered the amino acid at concentrations ranging from 0.068 to 1.35 g/kg body wt by oral gavage. Thirty minutes following the administration of doses of leucine as low as 0.135 g/kg body wt, skeletal muscle protein… CONTINUE READING
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