Oral irritation by mustard oil: self-desensitization and cross-desensitization with capsaicin.

@article{Simons2003OralIB,
  title={Oral irritation by mustard oil: self-desensitization and cross-desensitization with capsaicin.},
  author={Christopher T. Simons and Mirela Iodi Carstens and Earl E. Carstens},
  journal={Chemical senses},
  year={2003},
  volume={28 6},
  pages={459-65}
}
We investigated the temporal pattern of oral irritation elicited by sequential application of mustard oil (allyl-isothiocyanate), and whether it exhibits self-desensitization and cross-desensitization with capsaicin. Mustard oil (0.125%, 40 micro l) was sequentially applied to one side of the tongue at 1 min intervals, and subjects rated the intensity of the irritant sensation elicited by each stimulus. Ratings successively declined across trials, indicating desensitization. In contrast… CONTINUE READING

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