Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease.

@article{Higashi2009OralIP,
  title={Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease.},
  author={Yukihito Higashi and Chikara Goto and Takayuki Hidaka and Junko Soga and Shuji Nakamura and Yuichi Fujii and Takaki Hata and Naomi Idei and Noritaka Fujimura and Kazuaki Chayama and Yasuki Kihara and Akira Taguchi},
  journal={Atherosclerosis},
  year={2009},
  volume={206 2},
  pages={604-10}
}
OBJECTIVE Several studies have shown that periodontitis is a risk factor for cardiovascular diseases. There is an association between inflammation and endothelial dysfunction. The purpose of this study was to evaluate endothelial function in patients with coronary artery disease (CAD) who had periodontitis. METHODS AND RESULTS We evaluated forearm blood flow (FBF) responses to acetylcholine (ACh), an endothelium-dependent vasodilator, and to sodium nitroprusside (SNP), an endothelium… CONTINUE READING

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Periodontal infection is associated with endothelial dysfunction in humans. Hypertension

  • Y Higashi, D Jitsuiki, +10 authors A. Taguchi
  • 2008
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