Oral immunization of rainbow trout to infectious pancreatic necrosis virus (Ipnv) induces different immune gene expression profiles in head kidney and pyloric ceca.

@article{Ballesteros2012OralIO,
  title={Oral immunization of rainbow trout to infectious pancreatic necrosis virus (Ipnv) induces different immune gene expression profiles in head kidney and pyloric ceca.},
  author={Natalia A. Ballesteros and Sylvia S Rodr{\'i}guez Saint-Jean and Paloma A Encinas and Sara Isabel P{\'e}rez-Prieto and Julio Morales Coll},
  journal={Fish & shellfish immunology},
  year={2012},
  volume={33 2},
  pages={174-85}
}
Induction of neutralizing antibodies and protection by oral vaccination with DNA-alginates of rainbow trout Oncorhynchus mykiss against infectious pancreatic necrosis virus (IPNV) was recently reported. Because orally induced immune response transcript gene profiles had not been described yet neither in fish, nor after IPNV vaccination, we studied them in head kidney (an immune response internal organ) and a vaccine entry tissue (pyloric ceca). By using an oligo microarray enriched in immune… CONTINUE READING