Oral ibuprofen versus intravenous indomethacin for closure of patent ductus arteriosus in very low birth weight infants.

@article{Lee2012OralIV,
  title={Oral ibuprofen versus intravenous indomethacin for closure of patent ductus arteriosus in very low birth weight infants.},
  author={Cheng Han Lee and Hsiao-Neng Chen and L S Tsao and Chien-Chou Hsiao and M. -L. Lee},
  journal={Pediatrics and neonatology},
  year={2012},
  volume={53 6},
  pages={346-53}
}
BACKGROUND The purpose of this study is to compare the effects and complications of pharmacologic closure of patent ductus arteriosus (PDA) by intravenous indomethacin or oral ibuprofen in neonates weighing <1500 g at birth [very low birth weight (VLBW) infants]. METHODS This is a retrospective study of infants treated with intravenous indomethacin (0.2 mg/kg initially followed by two doses at 24-hour intervals) or oral ibuprofen (10 mg/kg initially followed an interval of 24 hours by two… CONTINUE READING