Oral human immunoglobulin for children with autism and gastrointestinal dysfunction: a prospective, open-label study.

@article{Schneider2006OralHI,
  title={Oral human immunoglobulin for children with autism and gastrointestinal dysfunction: a prospective, open-label study.},
  author={Cindy K Schneider and Raun D. Melmed and Leon E Barstow and Francisco Javier Jimenez Enriquez and James R. Ranger-Moore and James A. Ostrem},
  journal={Journal of autism and developmental disorders},
  year={2006},
  volume={36 8},
  pages={1053-64}
}
Immunoglobulin secretion onto mucosal surfaces is a major component of the mucosal immune system. We hypothesized that chronic gastrointestinal (GI) disturbances associated with autistic disorder (AD) may be due to an underlying deficiency in mucosal immunity, and that orally administered immunoglobulin would be effective in alleviating chronic GI dysfunction in these individuals. In this pilot study, twelve male subjects diagnosed with AD were evaluated using a GI severity index (GSI) while… CONTINUE READING

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