Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.

@article{Breda2001OralGT,
  title={Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.},
  author={Elena Breda and Melissa K. Cavaghan and Gianna Toffolo and Kenneth S. Polonsky and Claudio Cobelli},
  journal={Diabetes},
  year={2001},
  volume={50 1},
  pages={150-8}
}
The simultaneous assessment of quantitative indexes of insulin secretion and action in a single individual is important when quantifying their relative role in the evolution of glucose tolerance in different physiopathological states. Available methods quantify these indexes in relatively nonphysiological conditions, e.g., during glucose clamps or intravenous glucose tolerance tests. Here, we present a method based on a physiological test applicable to large-scale genetic and epidemiologic… CONTINUE READING
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