Corpus ID: 32531217

Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.

  title={Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.},
  author={E. Breda and M. Cavaghan and G. Toffolo and K. Polonsky and C. Cobelli},
  volume={50 1},
  • E. Breda, M. Cavaghan, +2 authors C. Cobelli
  • Published 2001
  • Medicine
  • Diabetes
  • The simultaneous assessment of quantitative indexes of insulin secretion and action in a single individual is important when quantifying their relative role in the evolution of glucose tolerance in different physiopathological states. Available methods quantify these indexes in relatively nonphysiological conditions, e.g., during glucose clamps or intravenous glucose tolerance tests. Here, we present a method based on a physiological test applicable to large-scale genetic and epidemiologic… CONTINUE READING

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