Oral glucosamine in doses used to treat osteoarthritis worsens insulin resistance.


BACKGROUND Glucosamine is used to treat osteoarthritis. In animals, the compound is known to cause insulin resistance, the underlying abnormality in type 2 diabetes mellitus. Insulin resistance in humans taking oral glucosamine in doses used for osteoarthritis has not been studied. METHODS Volunteer human subjects (n = 38) without known abnormality of… (More)


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