Oral gavage subchronic neurotoxicity and inhalation subchronic immunotoxicity studies of ethylbenzene in the rat.

@article{Li2010OralGS,
  title={Oral gavage subchronic neurotoxicity and inhalation subchronic immunotoxicity studies of ethylbenzene in the rat.},
  author={Abby A. Li and Jacques P J Maurissen and John F Barnett and John A Foss and Les Freshwater and Robert H. Garman and Vanessa L. Peachee and Sandra J Hong and Donald G. Stump and James S. Bus},
  journal={Neurotoxicology},
  year={2010},
  volume={31 3},
  pages={247-58}
}
The potential for neurotoxicological and immunotoxicological effects of ethylbenzene was studied in young adult Crl:CD(SD) rats following 90-day oral (neurotoxicity) or 28-day inhalation (immunotoxicity) exposures. In the neurotoxicity study, ethylbenzene was administered orally via gavage twice daily at 0, 25, 125, or 250 mg/kg per dose (total daily dosages of 0, 50, 250, or 500 mg/kg bwt/day [mg/kg bwt/day]) for 13 weeks and the functional observational battery (FOB), automated tests for… CONTINUE READING