Oral exposure to polystyrene nanoparticles affects iron absorption.

  title={Oral exposure to polystyrene nanoparticles affects iron absorption.},
  author={Gretchen J Mahler and Mandy Brigitte Esch and Elad Tako and Teresa L. Southard and Shivaun D Archer and Raymond Philip Glahn and Michael Louis Shuler},
  journal={Nature nanotechnology},
  volume={7 4},
The use of engineered nanoparticles in food and pharmaceuticals is expected to increase, but the impact of chronic oral exposure to nanoparticles on human health remains unknown. Here, we show that chronic and acute oral exposure to polystyrene nanoparticles can influence iron uptake and iron transport in an in vitro model of the intestinal epithelium and an in vivo chicken intestinal loop model. Intestinal cells that are exposed to high doses of nanoparticles showed increased iron transport… CONTINUE READING
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