Oral epithelial cells are susceptible to cell-free and cell-associated HIV-1 infection in vitro.

@article{Moore2003OralEC,
  title={Oral epithelial cells are susceptible to cell-free and cell-associated HIV-1 infection in vitro.},
  author={Jennifer S Moore and Firoz G Rahemtulla and Leigh W. Kent and Stacy D. Hall and Mine R Ikizler and Peter F Wright and Huan Huu Nguyen and Susan Jackson},
  journal={Virology},
  year={2003},
  volume={313 2},
  pages={343-53}
}
Epithelial cells lining the oral cavity are exposed to HIV-1 through breast-feeding and oral-genital contact. Genital secretions and breast milk of HIV-1-infected subjects contain both cell-free and cell-associated virus. To determine if oral epithelial cells can be infected with HIV-1 we exposed gingival keratinocytes and adenoid epithelial cells to cell-free virus and HIV-1-infected peripheral blood mononuclear cells and monocytes. Using primary isolates we determined that gingival… CONTINUE READING