Oral desensitization to 5-aminosalicylic acid medications.

  title={Oral desensitization to 5-aminosalicylic acid medications.},
  author={R C Stelzle and Edwara N Squire},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  volume={83 1},
BACKGROUND Although hypersensitive subjects have been desensitized to oral sulfasalazine, the feasibility of oral desensitization to the drug's active moiety, 5-aminosalicylic acid has been questioned and never been reported. METHODS We devised a 5-aminosalicylic acid desensitization protocol and administered the drug to two hypersensitive subjects on three occasions. RESULTS Both 5-aminosalicylic acid hypersensitive subjects were successfully desensitized without complications and were… CONTINUE READING

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