Oral delivery of purified lipoprotein OspA protects mice from systemic infection with Borrelia burgdorferi.

@article{Luke1997OralDO,
  title={Oral delivery of purified lipoprotein OspA protects mice from systemic infection with Borrelia burgdorferi.},
  author={C. Luke and R. Huebner and V. Kasmiersky and A. Barbour},
  journal={Vaccine},
  year={1997},
  volume={15 6-7},
  pages={
          739-46
        }
}
The lipoprotein outer surface protein A (OspA) of the Lyme disease agent. Borrelia burgdorferi, has provided protection to mice and other animals against systemic infection when delivered orally as a recombinant protein in Escherichia coli, bacille Calmette. Guerin or Salmonella typhimurium. In the present study purified recombinant strain B31 OspA or outer surface protein D (OspD), another lipoprotein of B. burgdorferi, were administered either subcutaneously (s.c.) or orally without cell… Expand
Role of Outer Surface Protein D in the Borrelia burgdorferi Life Cycle
...
1
2
3
4
...

References

SHOWING 1-10 OF 43 REFERENCES
Role of attached lipid in immunogenicity of Borrelia burgdorferi OspA.
...
1
2
3
4
5
...