Oral delivery of group A streptococcal cell walls augments circulating TGF-beta and suppresses streptococcal cell wall arthritis.

Abstract

Oral administration of autoantigens can influence the outcome of experimental autoimmune diseases, yet little is known about nonself Ag-induced tolerance. In this study, we administered group A streptococcal cell wall (SCW) peptidoglycan-polysaccharide complexes orally and monitored the impact on SCW-induced erosive polyarthritis. Oral administration of low… (More)

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Cite this paper

@article{Chen1998OralDO, title={Oral delivery of group A streptococcal cell walls augments circulating TGF-beta and suppresses streptococcal cell wall arthritis.}, author={W Chen and Wei Jin and M. Cook and H. L. Weiner and Sean M. Wahl}, journal={Journal of immunology}, year={1998}, volume={161 11}, pages={6297-304} }