Oral delivery of dsRNA lipoplexes to German cockroach protects dsRNA from degradation and induces RNAi response.

@article{Lin2017OralDO,
  title={Oral delivery of dsRNA lipoplexes to German cockroach protects dsRNA from degradation and induces RNAi response.},
  author={Yu-Hsien Lin and Jia-Hsin Huang and Yun Liu and Xavier Belles and How-Jing Lee},
  journal={Pest management science},
  year={2017},
  volume={73 5},
  pages={960-966}
}
BACKGROUND In the past years, the concept of RNAi application for insect pest control has been proposed, considering the disruption of vital genes. However, the efficiency of RNAi is variable between different insect groups, especially by oral delivery of dsRNA. The purpose of this study is to assess the possibilities of RNAi as a tool for pest control using oral delivery of the dsRNAs encapsulated by liposome in the German cockroach Blattella germanica, which is highly sensitive to RNAi by… CONTINUE READING
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