Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.

@article{Gookin2008OralDO,
  title={Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.},
  author={Jody L Gookin and D M Foster and Maria R Coccaro and Stephen H. Stauffer},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2008},
  volume={46 2},
  pages={139-46}
}
OBJECTIVES To determine if oral supplementation with L-arginine could augment nitric oxide (NO) synthesis and promote epithelial defense in neonatal piglets infected with Cryptosporidium parvum. MATERIALS AND METHODS Neonatal piglets were fed a liquid milk replacer and on day 3 of age infected or not with 10(8) C. parvum oocysts and the milk replacer supplemented with L-arginine or L-alanine. Milk consumption, body weight, fecal consistency, and oocyst excretion were recorded daily. On day 3… CONTINUE READING