Oral cytology assessment by flow cytometry of DNA adducts, aneuploidy, proliferation and apoptosis shows differences between smokers and non-smokers.

@article{Schwartz2003OralCA,
  title={Oral cytology assessment by flow cytometry of DNA adducts, aneuploidy, proliferation and apoptosis shows differences between smokers and non-smokers.},
  author={Joel L. Schwartz and Joshua E. Muscat and Vikki Baker and Eric Larios and Gina Day Stephenson and Wei Guo and Tianpei Xie and Xinbin Gu and Fung-Lung Chung},
  journal={Oral oncology},
  year={2003},
  volume={39 8},
  pages={842-54}
}
Oral cytology and morphometric staining is used to identify malignant keratinocytes in oral premalignant or malignant lesions. To detect and to begin to assess changes in oral keratinocytes exposed to tobacco-derived carcinogens, which are at risk for malignant transformation, a novel method is required. The approach uses oral cytology harvested oral keratinocytes analyzed using flow cytometry (FC) for changes in DNA content, damage, cell cycle and apoptosis. Six smoker and six non-smoker oral… CONTINUE READING