Oral carotenoids for photohypersensitivity in patients with erythrohepatic protoporphyria, polymorphous light eruptions and lupus erythematodes discoides.


beta-Carotene and canthaxanthin in a dose of 75--250 mg a day by mouth reduced the symptons of exposure to the sun in all 7 treated patients with erythrohepatic protoporphyria (EPP), in 15 of 18 with polymorphous light eruptions (PMLE) and in 3 of 4 with lupus erythematodes discoides. In the EPP group the protoporphyrin level tended to vary inversely with… (More)