Oral cannabinoids in people living with HIV on effective antiretroviral therapy: CTN PT028—study protocol for a pilot randomised trial to assess safety, tolerability and effect on immune activation

@inproceedings{Costiniuk2019OralCI,
  title={Oral cannabinoids in people living with HIV on effective antiretroviral therapy: CTN PT028—study protocol for a pilot randomised trial to assess safety, tolerability and effect on immune activation},
  author={Cecilia T Costiniuk and Zahra Saneei and Jean-Pierre Routy and Shari Margolese and Enrico Mandarino and Joel Singer and Bertrand Lebouch{\'e} and Joseph Cox and Jason Leslie Szabo and Marie-Jos{\'e}e M.D. Brouillette and Marina B Klein and Nicolas Chomont and Mohammad-Ali Jenabian},
  booktitle={BMJ open},
  year={2019}
}
INTRODUCTION Despite antiretroviral therapy (ART), people living with HIV have higher rates of non-infectious chronic diseases. These conditions are driven by relatively high levels of inflammation persisting on ART compared with uninfected individuals. Chronic inflammation also contributes to HIV persistence during ART. Cannabis when taken orally may represent a way to reduce inflammation and strengthen immune responses. Before planning large interventional studies, it is important to ensure… CONTINUE READING
35
Twitter Mentions

References

Publications referenced by this paper.
SHOWING 1-10 OF 96 REFERENCES

Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory Immune Cell Frequencies in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Individuals.

  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2018
VIEW 18 EXCERPTS
HIGHLY INFLUENTIAL

Endocannabinoids in the Gut

  • Cannabis and cannabinoid research
  • 2016
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Cannabis for the Management of Pain: Assessment of Safety Study (COMPASS).

  • The journal of pain : official journal of the American Pain Society
  • 2015
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…