Oral cancer plasma tumor marker identified with bead-based affinity-fractionated proteomic technology.

@article{Cheng2005OralCP,
  title={Oral cancer plasma tumor marker identified with bead-based affinity-fractionated proteomic technology.},
  author={A Cheng and Li-Chiu Chen and Kun-Yi Chien and Yin-Ju Chen and Joseph Tung-Chien Chang and H M Wang and Chun-ta Liao and I Chen},
  journal={Clinical chemistry},
  year={2005},
  volume={51 12},
  pages={2236-44}
}
BACKGROUND There is no plasma marker for detecting oral cancer, one of the most frequent cancers worldwide. We developed a bead-based affinity-fractionated proteomic method to discover a novel plasma marker for oral cancer. METHODS Affinity purification of heparinized plasma with magnetic beads and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis were used to screen potential oral cancer markers. We compiled MS protein profiles for 57… CONTINUE READING