Oral calcitriol for the treatment of persistent proteinuria in immunoglobulin A nephropathy: an uncontrolled trial.

@article{Szeto2008OralCF,
  title={Oral calcitriol for the treatment of persistent proteinuria in immunoglobulin A nephropathy: an uncontrolled trial.},
  author={Cheuk Chun Szeto and Kai-Ming Chow and Bonnie Ching-Ha Kwan and K H Carlos Chung and C. B. Leung and Philip Kam-tao Li},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2008},
  volume={51 5},
  pages={724-31}
}
BACKGROUND Laboratory research and previous retrospective study suggest that vitamin D and its analogues have profound effects on immune system function and glomerular mesangial cell proliferation. We conducted an open-label study to evaluate the antiproteinuric effect of calcitriol on proteinuria in patients with immunoglobulin A (IgA) nephropathy. STUDY DESIGN Open-label prospective uncontrolled trial. SETTING & PARTICIPANTS 10 patients (3 men) with biopsy-proven IgA nephropathy and… CONTINUE READING