Oral buffered esomeprazole is superior to i.v. pantoprazole for rapid rise of intragastric pH: a wireless pH metry analysis.

@article{Banerjee2010OralBE,
  title={Oral buffered esomeprazole is superior to i.v. pantoprazole for rapid rise of intragastric pH: a wireless pH metry analysis.},
  author={Rupa Banerjee and Duvvuru Nageshwar Reddy and Nalini M. Guda and Rakesh Kalpala and Swapna Mahurkar and Santosh Darisetty and Guduru Venkat Rao},
  journal={Journal of gastroenterology and hepatology},
  year={2010},
  volume={25 1},
  pages={43-7}
}
BACKGROUND AND AIMS A pH of more than 6 is required for clot stability and hemostasis. Intravenous proton pump inhibitors have a rapid onset of action compared to oral and have been preferred for management of non-variceal bleeding. Intravenous pantoprazole has been used extensively. Buffered esomeprazole (BE) is an oral preparation consisting of an inner core of non-enteric-coated esomeprazole with a shell of sodium bicarbonate. The buffer protects against acid degradation of esomeprazole in… CONTINUE READING

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