Oral bioaccessibility of dioxins/furans at low concentrations (50-350 ppt toxicity equivalent) in soil.

@article{Ruby2002OralBO,
  title={Oral bioaccessibility of dioxins/furans at low concentrations (50-350 ppt toxicity equivalent) in soil.},
  author={Michael V. Ruby and Kurt A Fehling and Dennis J Paustenbach and Bryce D Landenberger and Michael P. Holsapple},
  journal={Environmental science & technology},
  year={2002},
  volume={36 22},
  pages={4905-11}
}
Animal studies have indicated that the oral bioavailability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in environmentally contaminated soil could range from 0.5 to 60%. To estimate the oral bioavailability of TCDD, and the 16 other 2,3,7,8-substituted dioxin/furan congeners, this study used a physiologically based extraction test, designed around the anatomic and physiologic characteristics of the human digestive tract. This test measures the fraction of dioxins/furans in soil that would be… CONTINUE READING

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