Oral antiviral therapy improves the diagnostic accuracy of alpha-fetoprotein levels in patients with chronic hepatitis B.

@article{Shim2014OralAT,
  title={Oral antiviral therapy improves the diagnostic accuracy of alpha-fetoprotein levels in patients with chronic hepatitis B.},
  author={Jae-Jun Shim and Jung-Wook Kim and Chang Kyun Lee and Jae Young Jang and By Hwajung Kim},
  journal={Journal of gastroenterology and hepatology},
  year={2014},
  volume={29 9},
  pages={1699-705}
}
BACKGROUND AND AIMS Analysis of alpha-fetoprotein (AFP) levels affords limited diagnostic accuracy because of the high false-positive rates, especially in those with active chronic hepatitis B (CHB). We measured AFP levels before and after commencement of oral antiviral therapy and explored the utility of these data in terms of early detection of hepatocellular carcinoma (HCC) in patients with CHB. METHODS A total of 207 patients with CHB who were treated with an oral antiviral agent were… CONTINUE READING

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