Oral antidiabetic combination therapy with sulphonylureas and metformin.

Abstract

In a multicentre trial in general practice, a total of 1823 type 2 diabetics, not adequately controlled by diet and maximal sulphonylurea therapy, were treated with additional metformin 850--2 550 mg/d for 12 weeks. The average postprandial blood sugar decreased from 15.48 mmol/l to 10.43 mmol/l, HbA1 fell from 11.0% to 9.1%. Serum triglycerides decreased… (More)

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@article{Haupt1991OralAC, title={Oral antidiabetic combination therapy with sulphonylureas and metformin.}, author={Ernst Haupt and Bernhard Knick and T. Koschinsky and Hermann Liebermeister and J. Schneider and Herbert Hirche}, journal={Diabete & metabolisme}, year={1991}, volume={17 1 Pt 2}, pages={224-31} }