Oral and systemic factors associated with increased levels of human immunodeficiency virus type 1 RNA in saliva.

@article{Shugars2000OralAS,
  title={Oral and systemic factors associated with increased levels of human immunodeficiency virus type 1 RNA in saliva.},
  author={Diane C Shugars and Gary Douglas Slade and Lauren L. Patton and Susan A. Fiscus},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2000},
  volume={89 4},
  pages={432-40}
}
OBJECTIVE The purpose of this investigation was to quantify human immunodeficiency virus type-1 (HIV-1) RNA in saliva and plasma and identify factors associated with increased salivary viral load. STUDY DESIGN Forty HIV-1-seropositive adults underwent oral examinations to assess mucosal and periodontal health. Whole saliva was evaluated for HIV-1 RNA titer and occult blood. Plasma viral load, CD4 cell count, HIV-1 staging, and antiretroviral therapy data were obtained from medical records… CONTINUE READING