Oral and dental manifestations of vitamin D-dependent rickets type I: report of a pediatric case.

@article{Zambrano2003OralAD,
  title={Oral and dental manifestations of vitamin D-dependent rickets type I: report of a pediatric case.},
  author={Marlene Germania Leg{\~n}a Zambrano and Nikolaos G. Nikitakis and Mar{\'i}a del Carmen S{\'a}nchez-Quevedo and John J. Sauk and Heddie O. Sedano and Helen Rivera},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2003},
  volume={95 6},
  pages={
          705-9
        }
}
Vitamin D-dependent rickets type I (VDDRI) represents an autosomal recessive hereditary defect in vitamin D metabolism. Patients with VDDRI have mutations of chromosome 12 that affect the gene for the enzyme 1-alpha-hydroxylase, resulting in decreased levels of 1,25(OH)(2) vitamin D. Clinical features include growth failure, hypotonia, weakness, rachitic rosary, convulsions, tetany, open fontanels, and pathologic fractures. The oral and dental manifestations of VDDRI have not been described… 
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Long-term dental intervention and laboratory examination in a patient with Vitamin D-dependent rickets type I
TLDR
This case is the first to confirm amelogenesis imperfecta in a patient with VDDR-I that was not prevented by drug intervention, and it provides evidence that long-term dental intervention in patients with V ddr-I can result in an acceptable oral hygiene status.
Familial Vitamin D-dependent rickets Type 2A: A report of two cases with alopecia and oral manifestations
  • Moni Thakur
  • Medicine
    Journal of oral and maxillofacial pathology : JOMFP
  • 2019
TLDR
Two cases of familial VDDR2A, a rare autosomal recessive disorder caused by mutation in the Vitamin D receptor gene, leading to end-organ resistance to 1,25(OH)2Vitamin D3 are reported, with alopecia and oral manifestations.
Oral Rehabilitation of a Pediatric Patient with Vitamin D-dependent Rickets II: A Rare Case Report
TLDR
The case presented in this article is of vitamin D-dependent rickets type II in a pediatric dental patient who reported with multiple missing teeth and required treatment consisting of restorations and extractions.
Craniofacial and dental characteristics of patients with vitamin-D-dependent rickets type 1A compared to controls and patients with X-linked hypophosphatemia
TLDR
The craniofacial characteristics and the dental phenotype of patients with genetically confirmed VDDR1A are described, suggesting the combination of low availability of both calcium and phosphate to be critical in periods of enamel formation.
Dental management of patients with X-linked hypophosphatemia
TLDR
A 14 year old male and a 38 year old female with XLH were referred to the Department of Conservative Dentistry for endodontic treatment and the dental findings were periapical abscesses without obvious trauma or caries.
Dental Complications of Rickets in Early Childhood: Case Report on 2 Young Girls
TLDR
This case study presents 2 young girls with rickets in early childhood who suffered from subsequent serious tooth decay as a result of vitamin D deficiency.
Dental manifestations of patient with Vitamin D-resistant rickets
TLDR
The purpose of this article is to report a case of Vitamin D-resistant rickets in a 5 year-old boy, describing the dental findings and the treatment to be performed in these cases.
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Premature Exfoliation of Deciduous Teeth in a Four-Year-Old Child with Hypophosphatemic Rickets
TLDR
Dental alterations observed: spontaneous loss of teeth and hypoplastic structure of enamel and periodontal breakdown associated to the hypophosphatemic rickets are reported and discussed.
STOMATOLOGICAL/DENTAL FEATURES OF VITAMIN D RESISTANT AND VITAMIN D DEPENDENT RICKETS
TLDR
The incidence rates of insufficient physical development, body constitutional disorder, jaw shape, occlusion and teeth constitutional anomalies as well as delayed teeth eruption are significantly higher at vitamin D resistant rickets in comparison with vitamin D-dependent rickets and control group.
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TLDR
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Vitamin D-dependent rickets type I (VDDR-I), also known as pseudo-vitamin D-deficiency rickets, appears to result from deficiency of renal vitamin D 1alpha-hydroxylase activity. Prior work has shown…
Genetics of Vitamin D 1α-Hydroxylase Deficiency in 17 Families
Vitamin D-dependent rickets type I (VDDR-I), also known as pseudo-vitamin D-deficiency rickets, appears to result from deficiency of renal vitamin D 1alpha-hydroxylase activity. Prior work has shown…
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