Oral and Systemic Effects of Xylitol Consumption

@article{Janket2019OralAS,
  title={Oral and Systemic Effects of Xylitol Consumption},
  author={S J Janket and Jaspreet Benwait and Pauline Isaac and Leland K. Ackerson and Jukka H. Meurman},
  journal={Caries Research},
  year={2019},
  volume={53},
  pages={491 - 501}
}
Recent results of randomized trials testing the efficacy of xylitol in caries prevention have been conflicting. This narrative review reveals the sources of discrepancy. The following databases were searched for the terms “xylitol” or “artificial sweeteners” restricted to the English language: PubMed, Web of Science, Evidenced-Based Medicine, Scopus, and the Cochrane database. In a separate search, the terms “dental caries” or “cariogenicity” or “glucosyltransferase” or “low glycemic” or “low… Expand
9 Citations
Health benefits of xylitol
TLDR
Xylitol can reduce constipation, diabetes, obesity, and other body syndromes or illnesses; it has also revealed its stimulating effect on digestion and immune system; it can produce some side effects such as irritable bowel syndrome, diarrhea, nephrolithiasis, etc., when consumed in excessive amounts. Expand
A systematic review and meta-analysis of the role of sugar-free chewing gum on Streptococcus mutans
TLDR
There is a need for future research exploring the use of SFG as a preventive measure for reducing the cariogenic oral bacterial load, and the degree of variability in the effect and the moderate quality of the trials included are considered. Expand
Differences in Sweet Taste Perception and Its Association with the Streptococcus mutans Cariogenic Profile in Preschool Children with Caries
TLDR
The results of this study suggest the future use of taste preferences in children as a diagnostic tool for the early detection of increased susceptibility to caries through microbial dysbiosis towards specific species of microorganisms. Expand
Antimicrobial Activity, Biocompatibility and Anti-inflammatory Properties of Cetylpyridinium Chloride-based Mouthwash Containing Sodium Fluoride and Xylitol: An In Vitro Study.
TLDR
Using an oral epithelial cell model, the CPC-based mouthwashes were found to be less cytotoxic than a chlorhexidine-containing mouthwash used as control and to be biocompatible and to exhibit anti-inflammatory activity. Expand
Secondary oxalosis induced by xylitol concurrent with lithium-induced nephrogenic diabetes insipidus: a case report
TLDR
Patients receiving lithium therapy must be closely monitored during the perioperative period, and rehydration therapy using xylitol infusion should be avoided in such cases. Expand
Nonrestorative Management of Dental Caries
TLDR
Strategy adoption for the nonrestorative management of dental caries prolongs the life span of the teeth and sustains the good oral health of patients and is divided into four components to address the different etiological factors of dental Caries. Expand
Low-Glycemic-Index/Load Desserts Decrease Glycemic and Insulinemic Response in Patients with Type 2 Diabetes Mellitus
TLDR
Consumption of low-GI/GL dessert indicates a positive impact on metabolic parameters in T2DM patients, and hunger, additional food, and additional food quantity VAS ratings were significantly lower after the consumption of the low- GI/GLessert compared to control. Expand
Characterisation of a catalytic triad and reaction selectivity in the dual mechanism of the catalyse hydride transfer in xylitol phosphate dehydrogenase.
TLDR
The main goal of this work is to analyse the conformational changes of XPDH-bound ligands such as zinc, NADH, XU5P, and RU5P to elucidate the key amino acids involved in the substrate binding to increase the catalysis efficiency of xylitol production in the industry. Expand

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