Oral-aboral ectoderm differentiation of sea urchin embryos is disrupted in response to calcium ionophore.

@article{Akasaka1997OralaboralED,
  title={Oral-aboral ectoderm differentiation of sea urchin embryos is disrupted in response to calcium ionophore.},
  author={Koji Akasaka and Hiroaki Uemoto and F. Martin Wilt and Keiko Mitsunaga-Nakatsubo and Hiraku Shimada},
  journal={Development, growth & differentiation},
  year={1997},
  volume={39 3},
  pages={373-9}
}
Intracellular signaling mediated by calcium ions has been implicated as important in controlling cell activity. The ability of calcium ionophore (A23187), which causes an increase in calcium ion concentration in the cytoplasm, to alter the pattern of differentiation of cells during sea urchin development was examined. The addition of A23187 to embryos for 3 h during early cleavage causes dramatic changes in their development during gastrulation. Using tissue-specific cDNA probes and antibodies… CONTINUE READING
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