Oral Vitamin B12 Supplementation After Roux-en-Y Gastric Bypass: a Systematic Review

  title={Oral Vitamin B12 Supplementation After Roux-en-Y Gastric Bypass: a Systematic Review},
  author={K. Mahawar and Alastair Reid and Y. Graham and Lindes Callejas-Diaz and C. Parmar and W. R. Carr and N. Jennings and R. Singhal and P. Small},
  journal={Obesity Surgery},
BackgroundMany respectable guidelines recommend lifelong vitamin B12 injections for Roux-en-Y gastric bypass (RYGB) patients in the absence of lack of consensus on the efficacy of oral route of prophylaxis and the appropriate doses needed for this purpose. The purpose of this review was to examine the published English language scientific literature in accordance with PRISMA principles to find out if orally given vitamin B12 is adequate for prophylactic purposes in RYGB patients and the… Expand
Comments on: “Oral Vitamin B12 Supplementation After Roux-en-Y Gastric Bypass: a Systematic Review”
This review examines the effect of oral vitamin B12 supplementation for prophylaxis after Roux-en-Y gastric bypass and the appropriate dosages needed for this purpose and thinks the search methods of this review could have been improved. Expand
Micronutrients deficiences in patients after bariatric surgery
The present review summarizes some of the major vitamin and micronutrient deficiencies associated with bariatric surgery, particularly those presented post-surgically. Expand
Haemoglobin and Hematinic Status Before and After Bariatric Surgery over 4 years of Follow-Up
This study lends further support to regular supplementation with vitamin B12, folic acid, and iron in people undergoing bariatric surgery. Expand
Anaemia After One Anastomosis Gastric Bypass
The authors of this letter point out that others have found anaemia rates to be higher with SG than GB, Roux-en-Y gastric bypass in particular, and they further contend that the results might be due to the possibility that OAGB patients have a further reduction in capacity to absorb iron compared to those undergoing RYGB and this may well account for the suggested increase in anaemic rates following GB by Bailly et al. Expand
The Effects of Bariatric Surgery on Vitamin B Status and Mental Health
Considering the important functions of vitamin B and the severe consequences associated with its deficiency following bariatric surgery, proper dietary intervention and administration of adequate supplements should be considered to prevent negative clinical outcomes. Expand
One anastomosis gastric bypass: key technical features, and prevention and management of procedure-specific complications.
This review examines key technical steps of OAGB and presents evidence-based algorithms for prevention and management of marginal ulcers, protein-calorie malnutrition, and gastroesophageal reflux disease after OA GB. Expand
British Obesity and Metabolic Surgery Society Guidelines on perioperative and postoperative biochemical monitoring and micronutrient replacement for patients undergoing bariatric surgery—2020 update
  • M. O’Kane, H. Parretti, +14 authors J. Barth
  • Medicine
  • Obesity reviews : an official journal of the International Association for the Study of Obesity
  • 2020
These guidelines are comprehensive, encompassing preoperative and postoperative biochemical monitoring, vitamin and mineral supplementation and correction of nutrition deficiencies before, and following bariatric surgery, and make recommendations for safe clinical practice in the U.K. setting. Expand
Title: One Anastomosis Gastric Bypass-Key Technical Features, and Prevention and Management of Procedure-Specific Complications Short Title: One Anastomosis Gastric Bypass Authors:
Introduction: One Anastomosis Gastric Bypass (OAGB) is now a recognised mainstream bariatric procedure being adopted by an increasing number of surgeons. The purpose of this review was to present anExpand
Areas of Non-Consensus Around One Anastomosis/Mini Gastric Bypass (OAGB/MGB): A Narrative Review
There is enough evidence to include OAGB/MGB as an accepted standard bariatric and metabolic surgical procedure, however, long-term data and more research are needed to have a consensus in all aspects including these non-consensus topics. Expand
Ascertaining Areas for Long-Term Follow-Up of Bariatric Surgical Patients for Primary Care: A Narrative Review
Bariatric surgery is unique in terms of anatomical changes imposing a resetting of the physiological milieu, and many changes are beneficial, adverse effects, complications, and ... Expand


Optimization of Vitamin Suppletion After Roux-En-Y Gastric Bypass Surgery Can Lower Postoperative Deficiencies
An optimized multivitamin supplement is safe and reduces the development of iron and vitamin B12 deficiencies after LRYGB, and iron deficiency was reduced after WLS Forte compared with sMVS. Expand
Are vitamin B12 and folate deficiency clinically important after roux-en-Y gastric bypass?
Prophylactic oral iron supplements are recommended to premenopausal women who undergo RYGB to learn whether the risk of developmg these deficiencies decreases over time and to determine how readily patients who developed metabolic deficiencies after Roux-en-Y gastric bypass responded to postoperative supplements. Expand
Can Composite Nutritional Supplement Based on the Current Guidelines Prevent Vitamin and Mineral Deficiency After Weight Loss Surgery?
Use of a composite based on guidelines proposed by the AACE, TOS, and the ASMBS appears to be effective for preventing iron and vitamins A, B1, B12, and D deficiencies in the LRYGB patients during the first postoperative year. Expand
Anaemia and related nutrient deficiencies after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis
RYGB surgery is associated with an increased risk of anaemia and deficiencies of iron and vitamin B12, but not folate, andFerritin is more sensitive when serum iron level is within normal range. Expand
Treatment of Vitamin B12 Deficiency after Gastric Surgery for Severe Obesity
At least 350 μg per day is the appropriate oral dose of crystalline vitamin B 12 after gastric surgery for obesity to correct low serum vitamin B12 levels in 95% of patients. Expand
Effectiveness of B Vitamin Supplementation Following Bariatric Surgery: Rapid Increases of Serum Vitamin B12
Although energy intake decreased 64 %, B vitamin supplementation for 3 months resulted in a 48 % increase of serum vitamin B12, a modest increases of serum folate, and no reduction of blood thiamin concentrations. Expand
An optimized multivitamin supplement lowers the number of vitamin and mineral deficiencies three years after Roux-en-Y gastric bypass: a cohort study.
At 3 years postoperative of RYGB, an optimized multivitamin supplement (WLS Forte) was more effective in reducing anemia and ferritin, vitamin B12, and zinc deficiencies compared with a standard supplement and control. Expand
Anemia After Roux-en-Y Gastric Bypass. How Feasible to Eliminate the Risk by Proper Supplementation?
Frequency of anemia 1 year after RYGB in the population was low (4 %). Expand
Nutritional deficiencies after Roux-en-Y gastric bypass for morbid obesity often cannot be prevented by standard multivitamin supplementation.
BACKGROUND Despite the increasing use of Roux-en-Y gastric bypass (RYGBP) in the treatment of morbid obesity, data about postoperative nutritional deficiencies and their treatment remain scarce. Expand
Prevalence of Iron, Folate, and Vitamin B12 Deficiency Anemia After Laparoscopic Roux-en-Y Gastric Bypass
Routine scheme of vitamin supplementation is not sufficient to prevent iron and vitamin B12 deficiencies in most patients, and patients undergoing LRYGBP are likely to develop anemia. Expand