Oral Tolerance Therapy in Inflammatory Bowel Disease

@article{Hyun2006OralTT,
  title={Oral Tolerance Therapy in Inflammatory Bowel Disease},
  author={Jae Geun Hyun and Terrence A. Barrett},
  journal={The American Journal of Gastroenterology},
  year={2006},
  volume={101},
  pages={569-571}
}
Oral tolerance is a long-recognized method of inducing immune tolerance or systemic hyporesponsiveness induced by feeding protein. Oral tolerance has been used to prevent and/or treat a variety of T-cell-mediated autoimmune disorders. Feeding colonic extracts prevented colitis in animal model of inflammatory bowel disease (IBD), but the clinical efficacy of oral tolerance in human IBD was unknown. In this issue, the study by Margalit and colleagues suggested that oral administration of… CONTINUE READING

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