Oral Misoprostol Administration for Labor Induction

@article{Weeks2006OralMA,
  title={Oral Misoprostol Administration for Labor Induction},
  author={Andrew D. Weeks and Zarko Alfirevic},
  journal={Clinical Obstetrics and Gynecology},
  year={2006},
  volume={49},
  pages={658-671}
}
Using oral agents for induction of labor would reduce the need for repeated vaginal examinations; this is more acceptable to women and could reduce infection rates. A systematic review was conducted of 41 randomized trials comparing oral misoprostol to other induction agents. Oral misoprostol is effective at achieving vaginal delivery, and may have benefits over both vaginal and intracervical dinoprostone. Although it does not achieve vaginal delivery as quickly as vaginal misoprostol, the… Expand
Comparison of titrated oral misoprostol solution versus vaginal misoprostol for induction of labour in term obstetric patients for obstetric and neonatal outcomes: a randomized controlled trial
With more than 15% of all gravid women requiring aid in cervical ripening and labour induction, there is widespread interest in, and demand for, an effective and safe method of assistance. TheExpand
Titrated Oral Compared With Vaginal Misoprostol for Labor Induction: A Randomized Controlled Trial
TLDR
Titrated oral misoprostol is associated with a lower incidence of uterine hyperstimulation and a lower cesarean delivery rate than vaginal misop frostol for labor induction in patients with unfavorable cervix. Expand
Oral Misoprostol Versus Vaginal Prostaglandin E2 Labor Induction Efficiency, Safety, and Labor Outcomes
TLDR
The results showed that women who used oral misoprostol with an age less than 30 years and parity less than 3 was effective for delivery and safe outcomes with an odds ratio of 15.8, and present evidence does not support use of oral misOProstol versus Prostaglandin E2. Expand
Titrated misoprostol versus dinoprostone for labor induction
TLDR
Titrated misoprostol for induction of labor seems to be associated with significantly longer induction-to-delivery time, low incidence of vaginal birth within 24 h, and less need for augmentation of labor compared to vaginal dinoprostone. Expand
Outpatient oral misoprostol for prolonged pregnancies: a pilot investigation.
TLDR
Daily administration of oral misoprostol over 3 days to women with prolonged pregnancies shortened time intervals from dosing to entry into active labor and delivery compared with placebo. Expand
Misoprostol for Labour Induction after Previous Caesarean Section - Forever a "No Go"?
TLDR
The evidence supporting a ban on vaginal and particularly oral misoprostol for labour induction in the context of a scarred uterus is currently insufficient for a convincing guideline recommendation, so a retrospective review of registry data should be conducted to determine the incidence of uterine rupture following misopropol and the circumstances in which it occurs. Expand
Randomised controlled trial to compare safety and efficacy of vaginal versus oral route of misoprostol for induction of labour in term pregnancy with unfavourable cervix
TLDR
Oral misoprostol has a better safety profile than vaginal route as the incidence of hyperstimulation and tachysystole was significantly more in vaginal group, although there were no significant differences in the maternal and neonatal outcomes. Expand
Baixas doses de misoprostol vaginal (12,5 versus 25 mcg) para indução do parto a termo
TLDR
Vaginal misoprostol in the dose of 12.5 µg was efficient, with collateral effects similar, to the 25 µg of vaginal misOProstol, for induction of labor at term, in a double-blind, randomized, controlled clinical trial. Expand
Foley Catheter or Oral Misoprostol for Induction of Labor in Women with Term Premature Rupture of Membranes: A Randomized Multicenter Trial.
TLDR
Foley catheter or misoprostol can both be used for induction of labor in women with term premature rupture of membranes and the main outcomes were cesarean section and maternal and neonatal infections. Expand
How to Manage Labor Induction or Augmentation to Decrease the Cesarean Deliveries Rate
TLDR
There are many indications for term labor inductions and more than 15% of all gravid women require aid in cervical ripening and labor induction, and the immature cervix is the greatest barrier, which results in more concerned and unnecessary cesarean deliveries. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 54 REFERENCES
Oral or vaginal misoprostol for induction of labor
TLDR
The vaginal route of administration induced a higher success rate in a shorter time interval using a lower dose but was associated with more abnormal FHR patterns and instances of uterine hyperstimulation. Expand
A comparison of two dosage regimens of oral misoprostol for labor induction at term
TLDR
The primary outcome measure was the induction to delivery interval in those who delivered vaginally and patient satisfaction was assessed by postnatal questionnaire. Expand
Misoprostol vs. oxytocin for induction of labor at term
TLDR
Induction‐delivery interval was shorter with misoprostol but the rates of vaginal delivery, cesarean, neonatal outcome variables were similar, Hence, misopostol is an effective agent for induction of labor at term. Expand
Oral versus vaginal misoprostol for induction of labor: a double-blind randomized controlled trial.
TLDR
Vaginal misoprostol administered every 6 hours is more effective for induction of labor than oral misoportion administered every 3 hours, and the higher rates of tachysystole with use of vaginal misOProstol in the current study warrant further investigation. Expand
Oral misoprostol for induction of labour.
TLDR
Oral misoprostol appears to be more effective than placebo and at least as effective as vaginal dinoprostone for labour induction and there remain questions about its safety because of a relatively high rate of uterine hyperstimulation and the lack of appropriate dose ranging studies. Expand
Oral Versus Vaginal Misoprostol for Labor Induction
TLDR
Findings indicate that, in a closely supervised hospital setting with adequate monitoring, oral misoprostol has the potential to induce labor as safely and effectively as its vaginal analogue. Expand
Oral misoprostol or vaginal dinoprostone for labor induction: a randomized controlled trial.
TLDR
The authors found no difference in terms of effectiveness and safety between low-dose oral misoprostol and vaginal dinoprostone used for induction of labor and this regimen avoids the excessive uterine contractility noted in previous studies. Expand
Oral and Vaginal Misoprostol Compared With Dinoprostone for Induction of Labor: A Randomized Controlled Trial
TLDR
Vaginal misoprostol is as effective as dinoprostone in induction of labor, but it is associated with more tachysystole and cesarean sections for fetal distress compared with dinobrostone. Expand
A Masked Randomized Comparison of Oral and Vaginal Administration of Misoprostol for Labor Induction
TLDR
There is a shorter interval to vaginal birth with vaginal application; however, the more frequent occurrence of fetal heart rate graph abnormalities in this group suggests that, until the optimal dosing interval for vaginal use is determined, the preferred route of misoprostol administration might be oral. Expand
Oral misoprostol for premature rupture of membranes at term.
TLDR
In women at term with premature rupture of membranes, oral misoprostol resulted in a longer induction to vaginal delivery interval but increased maternal satisfaction and less hyperstimulation compared with intravenous oxytocin. Expand
...
1
2
3
4
5
...