Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure.

@article{BennettRichards2002OralLD,
  title={Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure.},
  author={Katy J Bennett-Richards and Mia Kattenhorn and Ann E. Donald and Gillian R Oakley and Zac Varghese and Karl Richard Bruckdorfer and John Erik Deanfield and Lesley Rees},
  journal={Kidney international},
  year={2002},
  volume={62 4},
  pages={
          1372-8
        }
}
BACKGROUND Cardiovascular disease is a major cause of mortality amongst patients with chronic renal failure (CRF). L-arginine has been used to improve endothelial function by increasing nitric oxide (NO) bioavailability and in animal models this in turn has attenuated the progression of atherosclerosis. We examined whether dietary L-arginine supplementation improved endothelial function in children with CRF. METHODS A randomized, double-blind, placebo-controlled, crossover trial of L-arginine… CONTINUE READING

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